Welcome to the International Surgical Outcomes Study (ISOS)

We are delighted to announce that the main ISOS report has now been accepted for publication in the British Journal of Anaesthesia. As the now leading international anaesthetic journal, this is an excellent platform for our work. All investigators have been named in the ISOS group included in the publication. The paper will be published on an open access basis, but you are free to download and read the final authors version here.

We have been working to present the most important insights from the ISOS data and are extremely pleased with the quality of data collection and analysis, this has lead to the publication of a number of additional papers as found below -

• International Surgical Outcomes Study group. Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries. Br J Anaesth. 2016; 117: 601-609. PMID: 27799174
• Kahan BC, Koulenti D, Arvaniti K, Beavis V, Campbell D, Chan M, Moreno R, Pearse RM; International Surgical Outcomes Study (ISOS) group. Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries. Intensive Care Med. 2017; 43: 971-979. PMID: 28439646
• Ahmad T, Bouwman RA, Grigoras I, Aldecoa C, Hofer C, Hoeft A, Holt P, Fleisher LA, Buhre W, Pearse RM; International Surgical Outcomes Study (ISOS) group. Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: a 7-day cohort study of elective surgery. Br J Anaesth. 2017; 119: 258-266. PMID: 28854536
• Szakmany T, Ditai J, Kirov M, Protsenko D, Osinaike B, Venara A, Demartines N, Hubner M, Pearse RM, Prowle JR; International Surgical Outcomes Study (ISOS) group. In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study. Eur J Surg Oncol. 2017 43: 2324-2332. PMID: 28916417
• Abbott TEF, Ahmad T, Phull MK, Fowler AJ, Hewson R, Biccard BM, Chew MS, Gillies M, Pearse RM; International Surgical Outcomes Study (ISOS) group. The surgical safety checklist and patient outcomes: a prospective observational cohort study, systematic review and meta-analysis. Br J Anaesth. 2018; 120: 146-155. PMID: 29397122
• Chaudery H, MacDonald N, Ahmad T, Chandra S, Tantri A, Sivasakthi V, Mansor M, Matos R, Pearse RM, Prowle JR; International Surgical Outcomes Study (ISOS) Group. Acute Kidney Injury and Risk of Death After Elective Surgery: Prospective Analysis of Data from an International Cohort Study. Anesth Analg. 2018. doi: 10.1213/ANE.0000000000003923. PMID: 30418232
• Fowler AJ, Ahmad T, Abbott TEF, Torrance HD, Wouters PF, De Hert S, Lobo SM, Rasmussen LS, Della Rocca G, Beattie WS, Wijeysundera DN, Pearse RM; International Surgical Outcomes Study Group. Association of preoperative anaemia with postoperative morbidity and mortality: an observational cohort study in low-, middle-, and high-income countries. Br J Anaesth. 2018; 121: 1227-1235. PMID: 30442249
• International Surgical Outcomes Study group. Prospective observational cohort study on grading the severity of postoperative complications in global surgery research. Br J Surg. 2019 Jan;106(2):e73-e80
• Wan YI, Patel A, Achary C, Hewson R, Phull M, Pearse RM. Postoperative infection and mortality following elective surgery in the International Surgical Outcomes Study (ISOS). British Journal of Surgery, Volume 108, Issue 2, February 2021, Pages 220–227

Thank you for your interest.

The ISOS study team

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Last updated: 18th May, 2021